Vascular permeability: the flow factor
نویسندگان
چکیده
منابع مشابه
Vascular permeability: the flow factor
Vascular permeability: the flow factor R ivers rarely run a smooth course. Blood vessels, just like rivers, have turns, tributaries and other obstacles that create eddies and other irregularities in the fl ow. In vessels, such areas of disturbed fl ow are more permeable and more prone to atherosclerotic plaques. Orr et al. (page 719) now reveal that a matrix protein that is abundant at such sit...
متن کاملPermeability Via Nitric Oxide and Prostacyclin Vascular Endothelial Growth Factor/Vascular Permeability Factor Enhances Vascular
50. Warren RS, Yuan H, Matli MR, Ferrara N, Donner DB. Induction of vascular endothelial growth factor by insulin-like growth factor 1 in colorectal carcinoma. J Biol Chem. 1996;271:29483–29488. 51. Dellian M, Witwer BP, Salehi HA, Yuan F, Jain RK. Quantitation and physiological characterization of angiogenic vessels in mice: effect of basic fibroblast growth factor, vascular endothelial growth...
متن کاملVascular endothelial growth factor/vascular permeability factor enhances vascular permeability via nitric oxide and prostacyclin.
BACKGROUND Vascular endothelial growth factor (VEGF), an endothelial cell mitogen that promotes angiogenesis, was initially identified as a vascular permeability factor (VPF). Abundant evidence suggests that angiogenesis is preceded and/or accompanied by enhanced microvascular permeability. The mechanism by which VEGF/VPF increases vascular permeability (VP), however, has remained enigmatic. Ac...
متن کاملVascular permeability factor of Pseudomonas aeruginosa.
The production of vascular permeability factor (PF) by certain strains of Pseudomonas aeruginosa has been demonstrated in rabbits injected intradermally with culture filtrates followed by intravenous injection with Pontamine Sky Blue 6BX. The dose-response curve was found to be rectilinear when lesion diameters, within the range of 10 to 20 mm, were plotted against log dose. Thus, PF in test fi...
متن کاملVascular permeability factor/vascular endothelial growth factor-mediated signaling in mouse mesentery vascular endothelium.
Vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) is a multifunctional cytokine and growth factor that has important roles in both pathological and physiological angiogenesis. VPF/VEGF induces vascular hyperpermeability, cell division, and other activities by interacting with two specific receptor tyrosine kinases, KDR/Flk-1 and Flt-1, that are selectively expressed on ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2007
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.1765iti2